Discovering a weak spot in the Corona virus may help eliminate it

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(Deutsche Welle)
Scientists' attempts to understand the Corona virus continue to be able to counter it, and in an American study , scientists have discovered a vulnerability of the virus that may help eradicate it.

Scientists' race continues overtime to find the appropriate vaccine or treatment to eliminate the Coronavirus. With each new study, information about the Coronavirus appears, helping the scientific community to better understand it and approaching another step in ridding the world of it.

One of these new studies has discovered new information about the way the virus multiplies in cells that may help scientists find a cure. According to the German Focus site, the American study showed that the Coronavirus forces the infected cells to develop what the team of scientists likened to "sensors" such as sensors (scientific name Filopodia) carrying the virus that can penetrate the shells of neighboring cells.

Sensors help the virus work in the body

The Reuters website explained the process in the cell after she was infected with the virus. When the new coronavirus enters a cell, it binds to enzymes called "kinase", which are enzymes that regulate the cell's activities. One of the enzymes that the kinase binds to the virus is called "CK2", which is the enzyme that the Coronavirus compels to produce sensors to transfer the virus to other cells.

Focus site quoted Nivan Crogan, one of the researchers from the University of California, America, that this method is what allows the new Coronavirus to spread quickly in the body, because these sensors allow the virus to infect a large number of cells at the same time.

The strength of the virus is also its weak point

 

The team of scientists based on the study, published in the scientific journal Cell, found that there are drugs to treat cancer that may prevent the Corona virus from forcing the CK2 enzyme to produce the sensors that penetrate other cells, so that doctors can penetrate the strength of the virus and use it against it. According to Live Science, there are about 87 drugs either on the market or under testing that can control these enzymes, particularly 7 drugs for the treatment of cancer and infections.

In experiments conducted by scientists, these drugs were able to prevent the spread of the virus in the cells of the kidneys of monkeys. According to Reuters, Marco Venusi, one of the study's authors from the Institut Pasteur in Paris, said that the use of enzyme inhibitors specifically targeting "CK2" may reduce or prevent the production of sensors, and thus this reduces the spread of the virus in the body.

Despite the promising result, Carol Rice, a biologist at New York University, warns of early joy. The Soester Anzeiger website reported that these experiments were carried out on monkeys only and not on cells of the human respiratory system. Therefore, it is now necessary to wait for the result of using these medications for people with HIV.

A promising German study

In a German study at the universities of Munich and Ulm, published in the scientific journal "Science", scientists also discovered new information on how the Coruna virus multiplies in cells. It is known that the virus attacks important parts of the immune system, the most important of which is its attack on the work of the so-called "ribosome", which is responsible for forming proteins in the cell, according to the website "Zoster Antsiger".

According to the site, the virus replaces the natural protein of the "ribosome" by producing a protein of its own, called "Nsp1", which stops the "ribosome" completely, paralyzing the work of an important defense line against the virus, according to scientists.

However, scientists hope this information will enable them to fight the virus, by developing a chemical molecule that can counter the viral protein "Nsp1". However, these studies are still in the early stages and need more time to bear fruit.